Abstract The Nuclear receptor 4A (NR4A) ranch style beans shirt subfamily, which belongs to the nuclear receptor (NR) superfamily, has three members: NR4A1 (Nur77), NR4A2 (Nurr1) and NR4A3 (Nor1).They are gene regulators with broad involvement in various signaling pathways and human disease responses, including autophagy.Here, we provide a concise overview of the current understanding of 2006 nissan altima radio the role of the NR4A subfamily members in human diseases and review the research into their regulation of cell autophagy.
A deeper understanding of these mechanisms has potential to improve drug development processes and disease therapy.